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Furthermore, closing the mechanistic knowledge gaps requires integrating multi-omics approaches (genomics, metabolomics, proteomics) with advanced computational modeling, that shall help identifying key bacterial strains, enzymes, and bioactive metabolites, moving from observational to predictive science (Liu X et al., 2025

Moreover, despite the reasonable sample size, the relatively small numbers of patients who experienced various clinical manifestations within the individual subgroups represented additional limitation

Smits, M

Protection against cisplatin-induced ototoxicity by n-acetylcysteine in a rat model